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As a result, follicular-fluid steroid concentrations and steroid ratios can diverge from serum values and may better approximate the hormonal context experienced by the oocyte-cumulus complex

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IGF-1 LR3 as a Probe: IGF-1 LR3 is employed in research to assess whether enhanced IGF-1type signaling can mitigate some of these catabolic signatures in specific models, providing insight into the crosstalk between glucocorticoid pathways and anabolic/repair pathways