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Most nodules are discovered incidentally during imagingonly 5-15% are malignant, but those larger than 4cm have higher cancer risk and cause compression symptoms

Tirzepatide , the active ingredient in both Mounjaro and Zepbound is currently being evaluated in phase 3 trials for cardiovascular outcomes in diabetes patients, heart failure with preserved ejection fraction, morbidity and mortality in obesity, and obstructive sleep apnea (OSA)

Overactivation of STAT3 skews the immune balance by promoting T helper 17 (Th17) cell expansion while suppressing Treg function