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176 In 1906, after the discovery of secretin, it was first tested if the gut aided the pancreas with disposing of nutrients via stimulation of pancreatic internal secretion by Moore and colleagues, who orally administered porcine small intestinal extract to treat diabetic patients
And the factor that most determines stability is inflammation
With obesity linked to hypertension, dyslipidemia, sleep apnea, cardiovascular disease, fatty liver disease, and kidney complications, GLP-1 drugs have become platform therapies rather than single-indication products
2019;14(5):e12495
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