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Conversely, Hantson and coworkers [83] recently reported the case of a 47-year-old epileptic man in whom parenteral VPA therapy was associated with a severe hyperammonaemic encephalopathy (peak ammonia concentration 411 mol/l) without any biological signs of hepatotoxicity

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In vivo ROS production and use of oxidative stress-derived biomarkers to detect the onset of diseases such as Alzheimers disease, Parkinsons disease, and diabetes