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Albiglutide (GlaxoSmithKline) is a fusion of two GLP-1 molecules with human albumin, which increases the proteolytic stability of GLP-1 and slows renal clearance, extending the half-life to 120 h
Together, they create a synergistic formulation ideal for studies in healing, muscle recovery, and soft tissue regeneration
Animal model studies consistently demonstrated that semaglutide can significantly alter gut microbiota, suggesting that part of semaglutides metabolic benefit may derive from its capacity to modulate inflammation via gut-immune-microbiota interactions and to correct dysbiosis induced by high-fat diets [82, 84]
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