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In line with these findings, the local anesthetic lidocaine has been proven to suppress the mRNA expression of SLC7A11 and to promote ferroptosis in ovarian and breast cancer cells in a dose-dependent manner, thereby repressing tumor growth [138]
In this study, we first demonstrated that retromer markers and VSRs localize to MVBs, suggesting that retrograde transport likely originates from MVBs (Supplementary Fig
5mg with 5mL = 1,000mcg/mL
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