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The numbers weve discussed are averages
Results published in The Lancet showed significant improvements in both weight and glycemic control (Rosenstock et al., 2023): Participants lost up to 16.9% of body weight (lower than the non-diabetic cohort, consistent with other medication studies) HbA1c reductions of up to 2.02 percentage points , bringing many participants into the normal range Significant improvements in fasting glucose and insulin sensitivity Phase 3 Trials Eli Lilly initiated Phase 3 clinical trials for retatrutide in late 2023
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In the most recent published trial, about 10% of people taking tirzepatide dropped out of the study because of such problems, compared to about 2% of people taking dummy shots
