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Finally, the dynamic crosstalk between microglia and other CNS cell types, including astrocytes, neurons, and endothelial cells, complicates the isolation of microglia-specific therapeutic effects

Photographic documentation from month 1 versus month 4 to 6 typically shows measurable differences in density at areas of prior thinning, particularly the temples, crown, and frontal hairline

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When DEGs were cross-referenced to a metabolic gene list (2,921 genes) compiled from previously published studies 6,32 , we observed significant overrepresentation of metabolic DEGs, as determined by Fishers exact test (Extended Data Fig