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DOI: 10.1038/s41423-022-00902-0

Challenges such as safety, dosage optimization, and long-term effects need to be thoroughly addressed before considering 5-Amino-1MQ as a viable anti-aging intervention for humans

Similarly, the protective effects of metformin on subchondral bone are indirect, occuring through cartilage integrity preservation and oxidative stress reduction 54

A 2024 narrative review synthesizing data across musculoskeletal applications further highlighted BPC-157s potential to promote controlled blood vessel growth and protect neuromuscular connections