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The Medicinal-Chemistry Disclosure (2021) The primary design paper describing cagrilintide was published by Andreassen and colleagues in the Journal of Medicinal Chemistry in 2021 [1]
This quickly boosts vitamin B12 levels in those who are low
While early and smaller trials showed promising fat-loss effects, the largest Phase IIb trial did not achieve statistical significance in humans for its primary endpoint of weight reduction, which led to the program being discontinued
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