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The connection to FOXO3 is direct and functionally significant: both FOXO3 and NRF2 independently activate GCLC, GCLM, and GPX1 expression through separate transcriptional pathways FOXO3 through forkhead response elements (FHREs) and NRF2 through AREs
Roager HM, Dragsted LO
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This process is called glycogenolysis and provides a short-term source of glucose when blood glucose levels are low, such as during an overnight fast or a bout of intense exercise (Matsui 2012
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