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Introduction Prader-Willi syndrome (PWS) is a complex, rare multisystem genetic disorder with an estimated prevalence of 1/10,0001/30,000 ( A complex hypothalamic-pituitary dysfunction is currently thought to be responsible for the entire PWS phenotype with implications on the endocrine and neurologic systems ( Due to their concomitant effect on glycemic control and body weight (BW), Glucagon-like Peptide 1 receptor agonists (GLP-1 RA) may represent an appealing option

Pickart L, Vasquez-Soltero JM, Margolina A GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration BioMed Research International (2015) 3

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