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194,195 The activated PI3K catalyzes the conversion of membrane phospholipid Phosphatidylinositol-4,5-bisphosphate (PIP2) into Phosphatidylinositol-3,4,5-trisphosphate (PIP3)
3,529 Accumulation of -synuclein in mitochondria can lead to the formation of oligomers that interact with mitochondrial membranes, inhibiting complex I activity and causing excessive mtROS production, which induces neuronal apoptosis
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