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Sitagliptin demonstrates selectivity for DPP-4 and does not inhibit DPP-8 or DPP-9 activity in vitro at concentrations approximating those from therapeutic doses
Too much sugar and fatty foods on these medications can sit extra heavy in your stomach and cause nausea or discomfort
28 Overall, we see significant growth opportunities within the GLP-1 category, driven by the expansion of supply to meet the high demand and anticipated approvals for new disease categories.
Lean mass loss is clinically relevant because it reduces physical function and resting metabolic rate, potentially amplifying compensatory responses and increasing susceptibility to weight regain ( GLP-1RAs are not designed to exert anabolic effects on skeletal muscle
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