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These ectopic receptors influence GLP-1, PYY and GIP secretion, serotonin and dopamine secretion, blood pressure, muscle regeneration, bone remodeling, bronchodilation, kidney function and many other physiological pathways
The before and after results with tirzepatide have been extensively documented, with many users reporting substantial changes in body composition, appetite patterns, and metabolic markers within the first months of treatment
This is especially true if you are losing weight quickly, noticing weakness, skipping breakfast, or relying mostly on crackers, toast, soup, or fruit because heavier foods feel unappealing
GLP-1 works in the brain to reduce appetite and slows down how quickly your stomach empties, keeping you fuller for longer
