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In user experience studies, up to 96.65% of participants reported a significant reduction in joint pain within just two weeks, along with improved mobility and daily comfort

This shift indicates a broader trend among insurers, where approximately 60% of plans include medications for obesity-related conditions, though stringent criteria often apply

Some may experience mild side effects such as nausea, which typically subsides as the body adjusts to the medication

Rosenstock et al., NEJM 2023), retatrutide begins to produce measurable effects on body weight and glycaemic markers within the first two to four weeks of treatment