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The brand became a cultural phenomenon through earned media, celebrity adoption, social commentary, and continuous news coverage

doi: 10.1038/ncomms13329 110 AgarwalPRashighiMEssienKIRichmondJMRandallLPazoki-ToroudiHet al

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Results demonstrated substantial reductions in liver fat content at 24 weeks across all active doses, with the 8 mg and 12 mg doses producing mean relative liver fat reductions of 81.4% and 82.4% respectively, compared to a +0.3% change with placebo