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Modulation of opioid transport at the blood-brain barrier by altered atp-binding cassette (ABC) transporter expression and activity

AWARD-6 is a randomized, open, parallel-grouped, multicenter, phase 3, non-inferiority study comparing the safety and efficacy of weekly DUL and daily LIR in patients with uncontrolled T2DM treated with metformin

These hybrids exhibited superior neuroprotective effects and lower cytotoxicity compared with curcumin alone, activated ARE, chelated ferrous ions and scavenged ROS, thereby protecting cells from oxidative stress and ferroptosis, ultimately promoting neuronal survival (104,127,128)

b , GLP-1R contacts formed with membrane lipids during molecular dynamic simulations of the GLP-1RTT-OAD2G s and the GLP-1RGLP-1G s systems