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The animal studies used both local application at the injury site and systemic administration (intraperitoneal and intragastric), with both routes showing significant effects

In my experience reviewing the GLP-1 class of drugs, elevated heart rate is a consistent finding across this entire drug family

Light Protection: Keep vials away from direct sunlight and strong artificial light sources

I think the direction of travel is the same, but there could be both an upside and a downside to our guidance depending on the pace of approval of generics in Canada. BMO does not expect the issue to spill over to the U.S