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Neither the disulfide lipoic acid (LA) nor GSSSG worked in this manner, and thus served as reliable controls in the high-dose experiments (Figure 1e bars 47 and Figure 2c,d)
5-Amino-1MQ , while still in early stages, has demonstrated compelling effects in preclinical models
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In a 26-week rat oral toxicity study, AOD-9604 produced dose-dependent changes in serum osteocalcin (a bone-turnover marker) at week 13, with the direction reversing by week 26
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