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Description

The underlying driver is chronic inflammationspecifically, dysregulated immune signaling involving TNF-, interleukins (IL-17, IL-23), and NF-B pathways

The most commonly reported adverse drug reactions (ADRs) associated with GLP-1 therapies are gastrointestinal, including nausea, diarrhea, constipation, and vomiting

Examples include: BCBS of Massachusetts has excluded Wegovy, Saxenda, and Zepbound from coverage for weight loss and other FDA-approved indications (such as sleep apnea and heart disease)