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B., Galli, L., Gati, C., Gutmann, M., Koglin, J., Markvardsen, A., Nass, K., Oberthur, D., Shoeman, R

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Together these residues tune the binding interface so that Ipamorelin engages the GHS-R1a receptor cleanly while showing minimal activity at the off-target receptors that drive cortisol, prolactin, and ACTH release

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Banoei MM, Lee CH, Hutchison J, Panenka W, Wellington C, Wishart DS, et al

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