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The VESPER trials, in plain English Pfizers VESPER program is structured around a practical question: can you get people through the highest-nausea part of GLP-1 therapy with weekly titration, then hold them on a monthly regimen without losing efficacy or tolerability
These drugs were created to treat type 2 diabetes, but have side effects that contribute to weight loss
Targeting sporadic and neurofibromatosis type 1 (NF1) related refractory malignant peripheral nerve sheath tumors (MPNST) in a phase II study of everolimus in combination with Bevacizumab (SARC016)
The observational study, led by Washington University clinical epidemiologist Dr Ziyad Al-Aly, analysed glucagon-like peptide 1 receptor agonists (GLP-1RAs), which have gained popularity in recent years as weight-loss drugs
