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We found that, regardless of the total dose of rHuEPO used, this substance improves the main hematological (total hemoglobin mass, hemoglobin concentration, and hematocrit) and physiological (maximal oxygen uptake and peak oxygen uptake) parameters, while the maximal performance-related parameters (mainly, maximal power output, and peak power output) also tend to increase

Ethics declarations Human and Animal Rights and Informed Consent This article does not contain any studies with human or animal subjects performed by any of the authors

Sustained exposure to 0.5 mM FeCl 3 induced a moderate loss of nearly 20% in iRPE cell viability over 24 h, a sustained alteration in cell integrity at 48 h, and continuous accumulation of intracellular iron at 48 h (Supplementary Fig