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SURMOUNT-5 was a phase 3b randomized controlled trial conducted at 32 sites across the United States and Puerto Rico.[1] A total of 751 adults with obesity but without type 2 diabetes were randomly assigned to receive either tirzepatide or semaglutide once weekly by subcutaneous injection for 72 weeks, which is just under 17 months.[1] Both medications were increased to the maximum tolerated dose

The pain might ease during enjoyable activities or worsen during stressful meetings, but it remains a constant background presence

Caloric Deficit Approach Eating fewer calories than your body burns each day is the basic rule of weight loss