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At maintenance, the effect is usually steadier and milder than the first-week change
Patients can present with the following signs & symptoms: CNS (areflexia, asthenia, ataxia, blurred vision, disorientation, dizziness, drowsiness, hyporeflexia, slurred speedh, somnolence, staggering, tiredness, coma) Cardiovascular (initial hypertension, followed by long-lasting hypotension , bradycardia , premature ventricular beats) the peripheral actions of xylazine cause an initial increase in blood pressure, followed by central effects that result in a long-lasting hypotensive effect, accompanied by bradycardia and reduced cardiac output (Hoffman et al, 2001)
While this process is reversible inside a cell, once it happens in a vial, the compound is effectively deactivated for your research purposes
Glutathione protects mitochondrial membranes and DNA from free radical damage 7
