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The most commonly reported adverse effects in Phase 2 trials were gastrointestinal in nature, including: Nausea (the most frequently reported) Vomiting Diarrhoea Constipation Decreased appetite These effects were generally dose-dependent and most pronounced during dose escalation, typically improving over time
(2016) conducted a targeted metabolomic analysis to investigate metabolic abnormalities in male participants, including 20 healthy controls (HC), 20 individuals with GWS (diagnosed using both Kansas and CDC criteria), and 22 ME/CFS patients from a previous cohort diagnosed with 2015 Institute of Medicine, CCC, and CDC-1994 diagnostic criteria
This provides baseline information about your metabolic health and can inform any adjustments needed as you transition off medication
What are the specific epigenetic factors involved in mitochondrial-nucleus communication
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