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Rather than directly activating GABA-A receptors, the peptide appears to maintain homeostasis of the entire GABA receptor complex, preventing the desensitization and compensatory changes that produce tolerance and dependence
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Reduced striatal dopamine transporter density in abstinent methamphetamine and methcathinone users: evidence from positron emission tomography studies with [11C]WIN-35,428
The peptide is hi ghly stable in gastric juice, allowing for potential oral bioavailability, and can also be administered via injection in preclinical studies
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