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If the reaction worsens over six weeks rather than improving, the problem is not the copper uglies

As GSH: GSSG serves as an accurate representation of cellular redox status it is also valuable as a biomarker for patient classification, active monitoring of treatment and the patients physiologic response, and an easily obtained measure of immune exhaustion or oxidative burden (Rossi et al., 2006

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In REDEFINE 2, which included participants with type 2 diabetes (a population that typically shows lower weight loss with any intervention), CagriSema achieved 13.7% weight loss compared to 3.4% with placebo