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Second-generation oral semaglutide, whose bioavailability and safety have been significantly improved by the application of new excipients and formulation optimization, but its gastrointestinal side effects are still obvious (Saxena et al., 2023)
THC, in particular, can stimulate your cravings for high-calorie foods, which are often the ones to avoid on Ozempic because they can increase GI side effects as well as derail any weight loss progress
At the same time, there is growing recognition that GLP-1 therapy reduces hepatic steatosis, triglycerides, and systemic inflammation
Moreover, EP supplementation ameliorated gut dysbiosis induced by high-fat diet, through the increase of short-chain fatty acid (SCFA)-producing bacteria and gut-barrier-protective microbe, and the reduction of endotoxin-producing bacteria [70]
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