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Studies have linked GLP-1 receptor agonists, including semaglutide (the active ingredient in Wegovy), to a higher incidence of gastroparesis and other gastrointestinal issues
GLP-1 binding to GLP-1R promotes -cell glucose metabolism through mTOR-dependent HIF-1 activation
doi: 10.1172/JCI72434 7 RasmussenMF
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