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A preclinical pilot study in human patients with chronic pain episodes found, that DSIP significantly reduced pain perception, also improved mood by reduction of depressive states, and that it may potentially be of interest for research into physiological addiction on pain medications, as it was observed to reduce withdrawal symptoms that occurs after discontinuation of long-term analgesic treatment

Residual metal in the flow path adds further irreproducibility

Vitamin B12 is completely water-soluble, meaning your body safely flushes out any excess, making toxicity non-existent

Khavinson VK, Bondarev IE, Butyugov AA