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Pernicious anemia occurs more commonly in people who already have diseases that are linked to immune-system abnormalities, such as Graves disease, hypothyroidism (under-functioning thyroid gland), thyroiditis (inflammation of the thyroid), vitiligo, and Addison's disease (adrenocortical insufficiency)

The effects may lead to joint pain and changes in glucose tolerance

Given the limited number of human clinical trials (only three published), the full side effect profile may not be completely characterized

It is the foundation that determines which peptides might work, why they work, and when they would be most useful