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Liraglutide (Saxenda) and semaglutide (Wegovy) are used within specialist weight management services as per NICE technology appraisals TA664 and TA875, with defined BMI and comorbidity criteria
Treatment begins with a subcutaneous injection of 0.25 mg once weekly for four weeks, followed by gradual dose escalation every four weeks: 0.5 mg, 1 mg, 1.7 mg, and finally the maintenance dose of 2.4 mg once weekly
Although 5-amino-1MQ displays high potential for clinical applications, quality data is still needed to establish its safety and efficacy
Stahl SM
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