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Basically, in some severe cases, it can cause a type of malnutrition, a symptom of which is fatigue
Its proposed mechanism of action includes stimulation of glucose-dependent insulin secretion, suppression of glucagon (via GLP-1), enhanced lipid metabolism (via GIP), and increased energy expenditure (via glucagon receptor activation)
The studies conducted on this topic suggest that allowing the body to use fat as a source of energy can lead to increased endurance since it is less glycogen dependent and fat utilization is improved
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