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Pharmacology 101: Activation of the GLP-1 receptor by GLP-1 RAs inhibits the release of the hormone motilin, which is important in stimulating gastric motility
In vitro investigations revealed its capacity to downregulate inflammatory gene expression and suppress the synthesis of interleukin 6 (IL-6), prostaglandin E2 and nitric oxide in chondrocytes and macrophages in a dose-dependent manner
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