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In the three-chamber test, MIA mice demonstrated a profound impairment in social interaction, as evidenced by a significantly lower sociability index score of 6.7 1.3, compared to 29.5 1.3 in control mice
The trial included more than 3,100 adults with obesity or a weight-related medical problem, excluding diabetes, and randomly assigned them to take a daily pill of either orforglipron or a placebo
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