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RNA-seq and subsequent gene set enrichment analysis (GSEA) revealed that the liver tissue from Gclc KO mice was enriched in several gene signatures associated with stress responses, including those related to the activation of NRF2 (Fig
, no significant effect in predefined outcome
This review aims to provide a comprehensive review of the current entero-pancreatic hormone-based therapies and emerging therapies emphasizing their mechanisms of action, clinical efficacy, and implications in addressing the global obesity epidemic
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