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GLP-1 receptor agonists carry a boxed warning about thyroid C-cell tumors based on animal studies with liraglutide
These outcomes matter for long-term health and mortality and should not be overshadowed by aesthetic or weight-loss narratives
Moreover, in terms of reduction in hemoglobin A1c (HbA1c) levels, the 50 mg dose of oral semaglutide outperformed the 14 mg dose, with reductions of 2.1% and 1.3%, respectively, at 68 weeks
The study found that both groups improved their glycaemic control and were able to reduce medication dosage in just 12 weeks (81)
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