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In athymic mice, 63% of exendin-4-treated mice achieved graft function compared with 21% of untreated mice (p = 0.033) in the short-term study
Two things are worth pulling out of that analysis
Apart from promoting weight reduction, semaglutide has been discovered to lower blood pressure in both diabetics and non-diabetics, likely due to its impact on weight loss and reduced insulin resistance
Cellular uptake of DiI-labelled LDL ( a ) or HDL ( b ) in HeLa cells, quantified by median PE fluorescence intensity (left) and shown in representative histograms (right)
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