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Frontiers in Sports and Active Living

1 As summarized in this review, resistance is not solely dictated by tumor-intrinsic genetic alterations but is shaped by a dynamic interplay among clonal evolution, signaling rewiring, epigenetic remodeling, altered DNA damage repair, metabolic adaptation, dysregulated cell death, TCP, microenvironmental remodeling, and hostmicrobetumor interactions

10.3748/wjg.v19.i42.7440 59 LiJ

Alzhaimers disease Alzhaimers disease (AD) is a chronic neurodegenerative disease characterized by the pathological accumulation of -amyloid peptides and neurofibrillary tangles into the brain, that usually starts slowly and gets worse over time up to dementia