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Considering the potential long-term public health challenges posed by AKD 38,39,40 , it is imperative for healthcare providers to incorporate GLP-1 RAs as an integral component of a comprehensive approach aimed at addressing this serious public health concern
However, the medication's glucose-lowering or weight-reducing effects may be diminished, leading to suboptimal glycemic control or inadequate weight loss
This dual mechanism, peripheral and central, is exactly why pyridoxine is such a logical addition to the formulation
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