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Lastly, niacinamide can be paired with glutathione, a tripeptide naturally present in the skin, known for its ability to modulate melanin synthesis by inhibiting tyrosinase and promoting a shift in melanogenesis toward the production of lighter pheomelanin
Does glutathione cause weight gain or weight loss
This shift may influence not only adherence but also long-term outcomes for patients at earlier stages of disease
That said, body weight can influence side effects and the pace of titration
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