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In the recent STEP HFpEF DM trial, which studied the efficacy of semaglutide among patients with obesity-related HF with preserved ejection fraction (HFpEF) and T2D, a reduction in the time to first HF events was demonstrated in the intervention arm, but this was a secondary endpoint
Management Strategies If injection site redness occurs, the patient must rotate their injection sites daily (moving between the stomach, thighs, and sides)
Use it twice a day, and massage it in for 30 seconds before rinsing
GLP-1 drugs were originally developed decades ago as diabetes treatments that alter the hormonal makeup of the brain and gut reducing hunger and slowing digestion
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