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Secondary efficacy measures included changes from baseline in: fast plasma glucose (FPG), postprandial plasma glucose (PPG), area under the curve, insulin, C-peptide, glucagon, insulin/proinsulin ratio, body measurements, and fasting lipid profiles

Discuss a clear plan for GLP-1 dose adjustments or temporary holds if intolerable gastrointestinal symptoms develop

It contrasts that with severe constipation lasting more than two weeks, which it treats as a different situation entirely and a reason to contact a provider rather than wait it out

There is no need for a second LC/MS injection for either reactive metabolite detection or recording of their MS/MS spectra