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Lancet 392 , 27052717 (2019)
In view of these mechanisms, combination therapy strategies can overcome drug resistance through multitarget synergy, regulating the TME, overcoming redox homeostasis, improving drug efficacy, and effectively reversing drug resistance
This histopathological hallmark enables the observation of lesion rims by MRI and correlates with high levels of serum neurofilament light chain, therefore with axonal injury, and with disease severity (141, 142)
Individual treatment decisions should be based on medical history, current evidence, medication availability, and provider judgment
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![PDF] Hepatotoxicity of paracetamol and related fatalities](https://figures.semanticscholar.org/56c82823292e7fd5d7f4ee9c6ceefc53147ef036/3-Figure1-1.png)
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