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Excessive Consumption : While moderate coffee intake may be beneficial, excessive consumption can lead to negative side effects, including anxiety, sleep disturbances, and gastrointestinal issues
PE treatment for 48 h was associated with significantly elevated ROS production relative to the levels observed in the control or PQQ treatment groups, while PQQ effectively reversed PE-induced ROS production (Figure 4A)
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It cannot be reliably used to prevent periods, and Norethisterone must not be added alongside it due to progestogen stacking
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