The honest status of AHK-Cu is a copper tripeptide with one ex-vivo / in-vitro study, a plausible mechanism borrowed from GHK-Cu, and no human data by any route [1] [2]
Its relaxing effect eases chronic pain, aids muscle recovery, reduces stress, and improves sleep quality
Therapy for a severe deficiency: 1000g Supply vs Intake: Not all Vitamin B12 can be Absorbed These rather high dosages are explained through the biological mechanism that enables the body to intake vitamin B12
Reported applications include NNMT enzyme inhibition assays measuring 1-methylnicotinamide formation or S-adenosylhomocysteine release, intracellular target-engagement assays in differentiated 3T3-L1 adipocytes where 5-Amino-1MQ reduced intracellular 1-methylnicotinamide with an EC near 2.3 M (Neelakantan et al., Biochem Pharmacol, 2018), membrane permeability and Caco-2 transport characterisation, methyltransferase selectivity panels covering COMT, DNMT1 and PRMT3, and rodent studies of NNMT inhibition in adipose tissue and liver following the antisense knockdown work of Kraus and colleagues (Nature, 2014)