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These escalation reactions typically resolve within 2 to 3 doses at the new level
Patients with a personal or family history of medullary thyroid carcinoma, those with multiple endocrine neoplasia type 2, or individuals with severe kidney disease may face contraindications
The studies investigating their effectiveness usually involved doses of 2 mcg/kg administered subcutaneously 2-3 times a day
GLP-1 receptor agonists solve this
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