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In the combined Phase 3 clinical trials anti-tesamorelin IgG antibodies were detected in 49.5% of patients treated with tesamorelin for 26 weeks and 47.4% of patients who received tesamorelin for 52 weeks

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Ipamorelin is unique among growth hormone releasing peptides in that, unlike most, it does not activate the bodys natural stress response

Fertil Steril 110(7):12981310 Bergan-Roller HE, Sheridan MA (2018) The growth hormone signaling system: insights into coordinating the anabolic and catabolic actions of growth hormone